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Phosphorylation of histone deacetylase 7 by protein kinase D mediates T cell receptor–induced Nur77 expression and apoptosis

The molecular basis of thymocyte negative selection, a crucial mechanism in establishing central tolerance, is not yet resolved. Histone deacetylases (HDACs) have emerged as key transcriptional regulators in several major developmental programs. Recently, we showed that the class IIa member, HDAC7,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dequiedt, Franck, Van Lint, Johan, Lecomte, Emily, Van Duppen, Viktor, Seufferlein, Thomas, Vandenheede, Jackie R., Wattiez, Ruddy, Kettmann, Richard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212830/
https://ncbi.nlm.nih.gov/pubmed/15738054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042034
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