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Inhibition of Histone Deacetylases Induces Bovine Leukemia Virus Expression In Vitro and In Vivo

Packaging into nucleosomes results in a global transcriptional repression as a consequence of exclusion of sequence-specific factors. This inhibition can be relieved by using inhibitors of histone deacetylases, acetylation being a major characteristic of transcriptionally active chromatin. Paradoxic...

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Hlavní autoři: Merezak, C., Reichert, M., Van Lint, C., Kerkhofs, P., Portetelle, D., Willems, L., Kettmann, R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136152/
https://ncbi.nlm.nih.gov/pubmed/11967319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.10.5034-5042.2002
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