The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection

Viral infection and stimulation with lipopolysaccharide (LPS) or double stranded RNA (dsRNA) induce phosphorylation of interferon (IFN) regulatory factor (IRF)-3 and its translocation to the nucleus, thereby leading to the IFN-β gene induction. Recently, two IκB kinase (IKK)–related kinases, inducib...

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Main Authors: Hemmi, Hiroaki, Takeuchi, Osamu, Sato, Shintaro, Yamamoto, Masahiro, Kaisho, Tsuneyasu, Sanjo, Hideki, Kawai, Taro, Hoshino, Katsuaki, Takeda, Kiyoshi, Akira, Shizuo
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2004
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212809/
https://ncbi.nlm.nih.gov/pubmed/15210742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040520
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