High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens

After vaccination of melanoma patients with MAGE antigens, we observed that even in the few patients showing tumor regression, the frequency of anti-vaccine T cells in the blood was often either undetectable or <10(−5) of CD8 T cells. This frequency being arguably too low for these cells to be so...

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Detalhes bibliográficos
Main Authors: Germeau, Catherine, Ma, Wenbin, Schiavetti, Francesca, Lurquin, Christophe, Henry, Emmanuelle, Vigneron, Nathalie, Brasseur, Francis, Lethé, Bernard, De Plaen, Etienne, Velu, Thierry, Boon, Thierry, Coulie, Pierre G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212796/
https://ncbi.nlm.nih.gov/pubmed/15657293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041379
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