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High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens

After vaccination of melanoma patients with MAGE antigens, we observed that even in the few patients showing tumor regression, the frequency of anti-vaccine T cells in the blood was often either undetectable or <10(−5) of CD8 T cells. This frequency being arguably too low for these cells to be so...

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Dettagli Bibliografici
Autori principali: Germeau, Catherine, Ma, Wenbin, Schiavetti, Francesca, Lurquin, Christophe, Henry, Emmanuelle, Vigneron, Nathalie, Brasseur, Francis, Lethé, Bernard, De Plaen, Etienne, Velu, Thierry, Boon, Thierry, Coulie, Pierre G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212796/
https://ncbi.nlm.nih.gov/pubmed/15657293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041379
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