BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma

We report that B cell–activating factor of the tumor necrosis factor (TNF) family (BAFF) is expressed in the normal human brain at ∼10% of that in lymphatic tissues (tonsils and adenoids) and is produced by astrocytes. BAFF was regularly detected by enzyme-linked immunosorbent assay in brain tissue...

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Detalhes bibliográficos
Main Authors: Krumbholz, Markus, Theil, Diethilde, Derfuss, Tobias, Rosenwald, Andreas, Schrader, Frank, Monoranu, Camelia-Maria, Kalled, Susan L., Hess, Donna M., Serafini, Barbara, Aloisi, Francesca, Wekerle, Hartmut, Hohlfeld, Reinhard, Meinl, Edgar
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212784/
https://ncbi.nlm.nih.gov/pubmed/15642740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041674
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