Expression of Herpes Simplex Virus 1-Encoded MicroRNAs in Human Trigeminal Ganglia and Their Relation to Local T-Cell Infiltrates

Herpes simplex type 1 (HSV-1) is a neurotropic virus which establishes lifelong latency in human trigeminal ganglia (TG). Currently, two nonexclusive control mechanisms of HSV-1 latency are discussed: antiviral CD8(+) T cells and viral microRNAs (miRNAs) encoded by the latency associated transcript...

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Détails bibliographiques
Auteurs principaux: Held, Kathrin, Junker, Andreas, Dornmair, Klaus, Meinl, Edgar, Sinicina, Inga, Brandt, Thomas, Theil, Diethilde, Derfuss, Tobias
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196425/
https://ncbi.nlm.nih.gov/pubmed/21795359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00874-11
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