Latent Herpes Simplex Virus 1 Infection Does Not Induce Apoptosis in Human Trigeminal Ganglia

Herpes simplex virus 1 (HSV-1) can establish lifelong latency in human trigeminal ganglia. Latently infected ganglia contain CD8(+) T cells, which secrete granzyme B and are thus capable of inducing neuronal apoptosis. Using immunohistochemistry and single-cell reverse transcription-quantitative PCR...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Himmelein, Susanne, Lindemann, Anja, Sinicina, Inga, Strupp, Michael, Brandt, Thomas, Hüfner, Katharina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442501/
https://ncbi.nlm.nih.gov/pubmed/25762734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03481-14
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