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Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration
Neurotrophin growth factors support neuronal survival and function. In this study, we show that the expression of the neurotrophin receptor TrkB is induced on astrocytes in white matter lesions in multiple sclerosis (MS) patients and mice with experimental autoimmune encephalomyelitis (EAE). Surpris...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302220/ https://ncbi.nlm.nih.gov/pubmed/22393127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110698 |
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