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Identification of poxvirus CD8(+) T cell determinants to enable rational design and characterization of smallpox vaccines

The large size of poxvirus genomes has stymied attempts to identify determinants recognized by CD8(+) T cells and greatly impeded development of mouse smallpox vaccination models. Here, we use a vaccinia virus (VACV) expression library containing each of the predicted 258 open reading frames to iden...

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書誌詳細
主要な著者: Tscharke, David C., Karupiah, Gunasegaran, Zhou, Jie, Palmore, Tara, Irvine, Kari R., Haeryfar, S.M. Mansour, Williams, Shanicka, Sidney, John, Sette, Alessandro, Bennink, Jack R., Yewdell, Jonathan W.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212779/
https://ncbi.nlm.nih.gov/pubmed/15623576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041912
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