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Conversion of CD4(+) CD25(−) cells into CD4(+) CD25(+) regulatory T cells in vivo requires B7 costimulation, but not the thymus

The CD4(+) CD25(+) regulatory T cells play a critical role in controlling autoimmunity, but little is known about their development and maintenance. In this study, we investigated whether CD4(+) CD25(−) cells can convert to CD4(+) CD25(+) regulatory T cells in vivo under natural conditions. CD4(+) C...

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Detaylı Bibliyografya
Asıl Yazarlar: Liang, Shuang, Alard, Pascale, Zhao, Yuan, Parnell, Sarah, Clark, Sherry L., Kosiewicz, Michele M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212775/
https://ncbi.nlm.nih.gov/pubmed/15630140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041201
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