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Production of single chain Fab (scFab) fragments in Bacillus megaterium

BACKGROUND: The demand on antigen binding reagents in research, diagnostics and therapy raises questions for novel antibody formats as well as appropriate production systems. Recently, the novel single chain Fab (scFab) antibody format combining properties of single chain Fv (scFv) and Fab fragments...

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Detalhes bibliográficos
Main Authors: Jordan, Eva, Al-Halabi, Laila, Schirrmann, Thomas, Hust, Michael, Dübel, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212634/
https://ncbi.nlm.nih.gov/pubmed/18042285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-6-38
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