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Production of single chain Fab (scFab) fragments in Bacillus megaterium

BACKGROUND: The demand on antigen binding reagents in research, diagnostics and therapy raises questions for novel antibody formats as well as appropriate production systems. Recently, the novel single chain Fab (scFab) antibody format combining properties of single chain Fv (scFv) and Fab fragments...

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Bibliographic Details
Main Authors: Jordan, Eva, Al-Halabi, Laila, Schirrmann, Thomas, Hust, Michael, Dübel, Stefan
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212634/
https://ncbi.nlm.nih.gov/pubmed/18042285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-6-38
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