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Production of single chain Fab (scFab) fragments in Bacillus megaterium

BACKGROUND: The demand on antigen binding reagents in research, diagnostics and therapy raises questions for novel antibody formats as well as appropriate production systems. Recently, the novel single chain Fab (scFab) antibody format combining properties of single chain Fv (scFv) and Fab fragments...

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Main Authors: Jordan, Eva, Al-Halabi, Laila, Schirrmann, Thomas, Hust, Michael, Dübel, Stefan
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212634/
https://ncbi.nlm.nih.gov/pubmed/18042285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-6-38
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