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Production of recombinant antibody fragments in Bacillus megaterium

BACKGROUND: Recombinant antibodies are essential reagents for research, diagnostics and therapy. The well established production host Escherichia coli relies on the secretion into the periplasmic space for antibody synthesis. Due to the outer membrane of Gram-negative bacteria, only a fraction of th...

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Bibliografische gegevens
Hoofdauteurs: Jordan, Eva, Hust, Michael, Roth, Andreas, Biedendieck, Rebekka, Schirrmann, Thomas, Jahn, Dieter, Dübel, Stefan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797049/
https://ncbi.nlm.nih.gov/pubmed/17224052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-6-2
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