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Analysis of Residues Near the Fusion Peptide in the Influenza Hemagglutinin Structure for Roles in Triggering Membrane Fusion

Influenza virus entry occurs in endosomes, where acidification triggers irreversible conformational changes of the hemagglutinin glycoprotein (HA) that are required for membrane fusion. The acid-induced HA structural rearrangements have been well documented, and several models have been proposed to...

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מידע ביבליוגרפי
Main Authors: Thoennes, Sudha, Li, Zhu-Nan, Lee, Byeong-Jae, Langley, William A., Skehel, John J., Russell, Rupert J., Steinhauer, David A.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212604/
https://ncbi.nlm.nih.gov/pubmed/17936324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.08.035
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