Infectivity Studies of Influenza Virus Hemagglutinin Receptor Binding Site Mutants in Mice

The replicative properties of influenza virus hemagglutinin (HA) mutants with altered receptor binding characteristics were analyzed following intranasal inoculation of mice. Among the mutants examined was a virus containing a Y98F substitution at a conserved position in the receptor binding site th...

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Detalhes bibliográficos
Main Authors: Meisner, Jeffrey, Szretter, Kristy J., Bradley, Konrad C., Langley, William A., Li, Zhu-Nan, Lee, Byeong-Jae, Thoennes, Sudha, Martin, Javier, Skehel, John J., Russell, Rupert J., Katz, Jacqueline M., Steinhauer, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346734/
https://ncbi.nlm.nih.gov/pubmed/18353965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01958-07
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