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Analysis of Residues Near the Fusion Peptide in the Influenza Hemagglutinin Structure for Roles in Triggering Membrane Fusion

Influenza virus entry occurs in endosomes, where acidification triggers irreversible conformational changes of the hemagglutinin glycoprotein (HA) that are required for membrane fusion. The acid-induced HA structural rearrangements have been well documented, and several models have been proposed to...

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Detalhes bibliográficos
Main Authors: Thoennes, Sudha, Li, Zhu-Nan, Lee, Byeong-Jae, Langley, William A., Skehel, John J., Russell, Rupert J., Steinhauer, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212604/
https://ncbi.nlm.nih.gov/pubmed/17936324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.08.035
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