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Analysis of Residues Near the Fusion Peptide in the Influenza Hemagglutinin Structure for Roles in Triggering Membrane Fusion

Influenza virus entry occurs in endosomes, where acidification triggers irreversible conformational changes of the hemagglutinin glycoprotein (HA) that are required for membrane fusion. The acid-induced HA structural rearrangements have been well documented, and several models have been proposed to...

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Bibliografiske detaljer
Main Authors: Thoennes, Sudha, Li, Zhu-Nan, Lee, Byeong-Jae, Langley, William A., Skehel, John J., Russell, Rupert J., Steinhauer, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212604/
https://ncbi.nlm.nih.gov/pubmed/17936324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.08.035
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