The Envelope Glycoprotein Ectodomains Determine the Efficiency of CD4(+) T Lymphocyte Depletion in Simian– Human Immunodeficiency Virus–Infected Macaques

CD4(+) T lymphocyte depletion in human immunodeficiency virus type 1 (HIV-1)–infected humans underlies the development of acquired immune deficiency syndrome. Using a model in which rhesus macaques were infected with chimeric simian–human immunodeficiency viruses (SHIVs), we show that both the level...

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Main Authors: Karlsson, Gunilla B., Halloran, Matilda, Schenten, Dominik, Lee, Juliette, Racz, Paul, Tenner-Racz, Klara, Manola, Judith, Gelman, Rebecca, Etemad-Moghadam, Bijan, Desjardins, Elizabeth, Wyatt, Richard, Gerard, Norma P., Marcon, Luisa, Margolin, David, Fanton, John, Axthelm, Michael K., Letvin, Norman L., Sodroski, Joseph
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212530/
https://ncbi.nlm.nih.gov/pubmed/9743534
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