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Immunoglobulin V(H) usage during primary infection of rhesus monkeys with chimeric simian-human immunodeficiency viruses.

It has been suggested that naive immunoglobulins encoded by the V(H)3 gene family interact aberrantly with human immunodeficiency virus type 1 (HIV-1) gp120 via a superantigenic epitope, causing initial expansion and eventual depletion of V(H)3-expressing B cells. However, this possibility has not b...

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Autors principals: Margolin, D H, Reimann, K A, Sodroski, J, Karlsson, G B, Tenner-Racz, K, Racz, P, Letvin, N L
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC192322/
https://ncbi.nlm.nih.gov/pubmed/9343216
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