Transgenic Mice Overexpressing the Complement Inhibitor Crry as a Soluble Protein Are Protected from Antibody-induced Glomerular Injury

Complement receptor 1–related gene/protein y (Crry) is a potent murine membrane complement regulator that inhibits classical and alternative pathway C3 convertases. In nephrotoxic serum (NTS) nephritis, injected antibodies (Abs) bind to glomeruli, leading to complement activation and subsequent glom...

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Main Authors: Quigg, Richard J., He, Chun, Lim, Alice, Berthiaume, Dawn, Alexander, Jessy J., Kraus, Damian, Michael Holers, V.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212499/
https://ncbi.nlm.nih.gov/pubmed/9763611
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