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Increased serum C3 levels in Crry transgenic mice partially abrogates its complement inhibitory effects
Complement receptor 1-related gene/protein y (Crry) is a potent murine complement regulator that inhibits C3 convertases. Transgenic mice that overexpress soluble Crry (sCrry), directed systemically by the metallothionein-I promoter, have been used as an animal model for chronic blockade of compleme...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1809028/ https://ncbi.nlm.nih.gov/pubmed/15086380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02450.x |
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