Natural Killer (NK) Cell–mediated Cytotoxicity: Differential Use of  TRAIL and Fas Ligand by Immature and Mature Primary Human NK Cells

Mature natural killer (NK) cells use Ca(2+)-dependent granule exocytosis and release of cytotoxic proteins, Fas ligand (FasL), and membrane-bound or secreted cytokines (tumor necrosis factor [TNF]-α) to induce target cell death. Fas belongs to the TNF receptor family of molecules, containing a conse...

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Bibliografiske detaljer
Main Authors: Zamai, Loris, Ahmad, Manzoor, Bennett, Ian M., Azzoni, Livio, Alnemri, Emad S., Perussia, Bice
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1998
Fag:
Brief Definitive Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212426/
https://ncbi.nlm.nih.gov/pubmed/9858524
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