Human decidual NK cells form immature activating synapses and are not cytotoxic

In early pregnancy invading fetal trophoblasts encounter abundant maternal decidual natural killer cells (dNK). dNK express perforin, granzymes A and B and the activating receptors NKp30, NKp44, NKp46, NKG2D, and 2B4 as well as LFA-1. Even though they are granular and express the essential molecules...

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Detalhes bibliográficos
Main Authors: Kopcow, Hernan D., Allan, David S. J., Chen, Xi, Rybalov, Basya, Andzelm, Milena M., Ge, Baoxue, Strominger, Jack L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266146/
https://ncbi.nlm.nih.gov/pubmed/16230631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507835102
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