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TGFβ promotes conversion of CD16(+) peripheral blood NK cells into CD16(−) NK cells with similarities to decidual NK cells

During pregnancy the uterine decidua is populated by large numbers of natural killer (NK) cells with a phenotype CD56(superbright)CD16(−)CD9(+)KIR(+) distinct from both subsets of peripheral blood NK cells. Culture of highly purified CD16(+)CD9(−) peripheral blood NK cells in medium containing TGFβ1...

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Hlavní autoři: Keskin, Derin B., Allan, David S. J., Rybalov, Basya, Andzelm, Milena M., Stern, Joel N. H., Kopcow, Hernan D., Koopman, Louise A., Strominger, Jack L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805591/
https://ncbi.nlm.nih.gov/pubmed/17360654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611098104
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