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The JNK Pathway Regulates the In Vivo Deletion of Immature CD4(+)CD8(+) Thymocytes

The extracellular signal-regulated kinase (ERK), the c-Jun NH(2)-terminal kinase (JNK), and p38 MAP kinase pathways are triggered upon ligation of the antigen-specific T cell receptor (TCR). During the development of T cells in the thymus, the ERK pathway is required for differentiation of CD4(−)CD8...

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Autors principals: Rincón, Mercedes, Whitmarsh, Alan, Yang, Derek D., Weiss, Linda, Dérijard, Benoit, Jayaraj, Prash, Davis, Roger J., Flavell, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212412/
https://ncbi.nlm.nih.gov/pubmed/9815259
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