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HIV-1 Variation Diminishes CD4 T Lymphocyte Recognition

Effective long-term antiviral immunity requires specific cytotoxic T lymphocytes and CD4(+) T lymphocyte help. Failure of these helper responses can be a principle cause of viral persistence. We sought evidence that variation in HIV-1 CD4(+) T helper epitopes might contribute to this phenomenon. To...

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Detalhes bibliográficos
Main Authors: Harcourt, Gillian C., Garrard, Sarah, Davenport, Miles P., Edwards, Anne, Phillips, Rodney E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212407/
https://ncbi.nlm.nih.gov/pubmed/9815256
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