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HIV-1–specific CD4(+) T lymphocyte turnover and activation increase upon viral rebound

HIV-specific CD4(+) T helper lymphocytes are preferred targets for infection. Although complete interruption of combination antiretroviral therapy (ART) can form part of therapeutic manipulations, there is grave concern that the resumption of viral replication might destroy, perhaps irreversibly, th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Scriba, Thomas J., Zhang, Hua-Tang, Brown, Helen L., Oxenius, Annette, Tamm, Norbert, Fidler, Sarah, Fox, Julie, Weber, Jonathan N., Klenerman, Paul, Day, Cheryl L., Lucas, Michaela, Phillips, Rodney E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC544605/
https://ncbi.nlm.nih.gov/pubmed/15668739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523084
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