HIV-1–specific CD4(+) T lymphocyte turnover and activation increase upon viral rebound

HIV-specific CD4(+) T helper lymphocytes are preferred targets for infection. Although complete interruption of combination antiretroviral therapy (ART) can form part of therapeutic manipulations, there is grave concern that the resumption of viral replication might destroy, perhaps irreversibly, th...

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Detalhes bibliográficos
Main Authors: Scriba, Thomas J., Zhang, Hua-Tang, Brown, Helen L., Oxenius, Annette, Tamm, Norbert, Fidler, Sarah, Fox, Julie, Weber, Jonathan N., Klenerman, Paul, Day, Cheryl L., Lucas, Michaela, Phillips, Rodney E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544605/
https://ncbi.nlm.nih.gov/pubmed/15668739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523084
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