Vaccination with DNA Encoding an Immunodominant Myelin Basic Protein Peptide Targeted to Fc of Immunoglobulin G Suppresses Experimental Autoimmune Encephalomyelitis

We explore here if vaccination with DNA encoding an autoantigenic peptide can suppress autoimmune disease. For this purpose we used experimental autoimmune encephalomyelitis (EAE), which is an autoaggressive disease in the central nervous system and an animal model for multiple sclerosis. Lewis rats...

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Main Authors: Lobell, Anna, Weissert, Robert, Storch, Maria K., Svanholm, Cecilia, de Graaf, Katrien L., Lassmann, Hans, Andersson, Roland, Olsson, Tomas, Wigzell, Hans
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 1998
主題:
Brief Definitive Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212261/
https://ncbi.nlm.nih.gov/pubmed/9565646
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