Vaccination with DNA Encoding an Immunodominant Myelin Basic Protein Peptide Targeted to Fc of Immunoglobulin G Suppresses Experimental Autoimmune Encephalomyelitis

We explore here if vaccination with DNA encoding an autoantigenic peptide can suppress autoimmune disease. For this purpose we used experimental autoimmune encephalomyelitis (EAE), which is an autoaggressive disease in the central nervous system and an animal model for multiple sclerosis. Lewis rats...

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Autors principals: Lobell, Anna, Weissert, Robert, Storch, Maria K., Svanholm, Cecilia, de Graaf, Katrien L., Lassmann, Hans, Andersson, Roland, Olsson, Tomas, Wigzell, Hans
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1998
Matèries:
Brief Definitive Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212261/
https://ncbi.nlm.nih.gov/pubmed/9565646
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