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Protective DNA vaccination against organ-specific autoimmunity is highly specific and discriminates between single amino acid substitutions in the peptide autoantigen

DNA vaccines that encode encephalitogenic sequences in tandem can protect from subsequent experimental autoimmune encephalomyelitis induced with the corresponding peptide. The mechanism for this protection and, in particular, if it is specific for the amino acid sequence encoding the vaccine are not...

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Detalhes bibliográficos
Main Authors: Weissert, Robert, Lobell, Anna, de Graaf, Katrien L., Eltayeb, Sana Yousif, Andersson, Roland, Olsson, Tomas, Wigzell, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26497/
https://ncbi.nlm.nih.gov/pubmed/10677519
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