Protective DNA vaccination against organ-specific autoimmunity is highly specific and discriminates between single amino acid substitutions in the peptide autoantigen

DNA vaccines that encode encephalitogenic sequences in tandem can protect from subsequent experimental autoimmune encephalomyelitis induced with the corresponding peptide. The mechanism for this protection and, in particular, if it is specific for the amino acid sequence encoding the vaccine are not...

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Hlavní autoři: Weissert, Robert, Lobell, Anna, de Graaf, Katrien L., Eltayeb, Sana Yousif, Andersson, Roland, Olsson, Tomas, Wigzell, Hans
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC26497/
https://ncbi.nlm.nih.gov/pubmed/10677519
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