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Ca(2+) Signaling Modulates Cytolytic T Lymphocyte Effector Functions
Cytolytic T cells use two mechanisms to kill virally infected cells, tumor cells, or other potentially autoreactive T cells in short-term in vitro assays. The perforin/granule exocytosis mechanism uses preformed cytolytic granules that are delivered to the target cell to induce apoptosis and eventua...
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Main Authors: | , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
The Rockefeller University Press
1998
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212215/ https://ncbi.nlm.nih.gov/pubmed/9529322 |
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