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Mucosal Adjuvanticity and Immunogenicity of LTR72, a Novel Mutant of Escherichia coli Heat-labile Enterotoxin with Partial Knockout of ADP-ribosyltransferase Activity

Heat-labile Escherichia coli enterotoxin (LT) has the innate property of being a strong mucosal immunogen and adjuvant. In the attempt to reduce toxicity and maintain the useful immunological properties, several LT mutants have been produced. Some of these are promising mucosal adjuvants. However, s...

詳細記述

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書誌詳細
主要な著者: Giuliani, Marzia Monica, Del Giudice, Giuseppe, Giannelli, Valentina, Dougan, Gordon, Douce, Gill, Rappuoli, Rino, Pizza, Mariagrazia
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212201/
https://ncbi.nlm.nih.gov/pubmed/9529328
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