Caspase-mediated Cleavage of Focal Adhesion Kinase pp125(FAK) and Disassembly of Focal Adhesions in Human Endothelial Cell Apoptosis

Normal endothelial and epithelial cells undergo apoptosis when cell adhesion and spreading are prevented, implying a requirement for antiapoptotic signals from the extracellular matrix for cell survival. We investigated some of the molecular changes occurring in focal adhesions during growth factor...

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Main Authors: Levkau, Bodo, Herren, Barbara, Koyama, Hidenori, Ross, Russell, Raines, Elaine W.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1998
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212148/
https://ncbi.nlm.nih.gov/pubmed/9463408
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