Focal adhesion kinase (pp125FAK) cleavage and regulation by calpain.

Focal adhesion kinase (125 kDa form; pp125FAK) is a widely expressed non-receptor tyrosine kinase that is implicated in integrin-mediated signal transduction. We have identified a novel means of pp 125FAK regulation in human platelets, in which this kinase undergoes sequential proteolytic modificati...

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Autores principales: Cooray, P, Yuan, Y, Schoenwaelder, S M, Mitchell, C A, Salem, H H, Jackson, S P
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217586/
https://ncbi.nlm.nih.gov/pubmed/8761450
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