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Degraded Collagen Fragments Promote Rapid Disassembly of Smooth Muscle Focal Adhesions That Correlates with Cleavage of Pp125(FAK), Paxillin, and Talin

Active matrix metalloproteinases and degraded collagen are observed in disease states, such as atherosclerosis. To examine whether degraded collagen fragments have distinct effects on vascular smooth muscle cells (SMC), collagenase-digested type I collagen was added to cultured human arterial SMC. A...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Carragher, Neil O., Levkau, Bodo, Ross, Russell, Raines, Elaine W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151179/
https://ncbi.nlm.nih.gov/pubmed/10545505
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