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Inhibition of Apoptosis in Chlamydia-infected Cells: Blockade of Mitochondrial Cytochrome c Release and Caspase Activation

We report that chlamydiae, which are obligate intracellular bacterial pathogens, possess a novel antiapoptotic mechanism. Chlamydia-infected host cells are profoundly resistant to apoptosis induced by a wide spectrum of proapoptotic stimuli including the kinase inhibitor staurosporine, the DNA-damag...

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Autori principali: Fan, Tao, Lu, Hang, Hu, He, Shi, Lianfa, McClarty, Grant A., Nance, Dwight M., Greenberg, Arnold H., Zhong, Guangming
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212145/
https://ncbi.nlm.nih.gov/pubmed/9463399
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