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Caspase cleavage of cytochrome c1 disrupts mitochondrial function and enhances cytochrome c release

Mitochondrial catastrophe can be the cause or consequence of apoptosis and is associated with a number of pathophysiological conditions. The exact relationship between mitochondrial catastrophe and caspase activation is not completely understood. Here we addressed the underlying mechanism, explainin...

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Detalhes bibliográficos
Main Authors: Zhu, Yushan, Li, Min, Wang, Xiaohui, Jin, Haijing, Liu, Shusen, Xu, Jianxin, Chen, Quan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351920/
https://ncbi.nlm.nih.gov/pubmed/21577235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.82
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