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Shifts in targeting of class switch recombination sites in mice that lack μ switch region tandem repeats or Msh2

The mechanisms that target class switch recombination (CSR) to antibody gene switch (S) regions are unknown. Analyses of switch site locations in wild-type mice and in mice that lack the Sμ tandem repeats show shifts indicating that a 4–5-kb DNA domain (bounded upstream by the Iμ promoter) is access...

詳細記述

保存先:
書誌詳細
主要な著者: Min, Irene M., Rothlein, Lisa R., Schrader, Carol E., Stavnezer, Janet, Selsing, Erik
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212040/
https://ncbi.nlm.nih.gov/pubmed/15955838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042491
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