Positive and Negative Regulation of FcɛRI-Mediated Signaling by the Adaptor Protein LAB/NTAL

Linker for activation of B cells (LAB, also called NTAL; a product of wbscr5 gene) is a newly identified transmembrane adaptor protein that is expressed in B cells, NK cells, and mast cells. Upon BCR activation, LAB is phosphorylated and interacts with Grb2. LAB is capable of rescuing thymocyte deve...

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Bibliographic Details
Main Authors: Zhu, Minghua, Liu, Yan, Koonpaew, Surapong, Granillo, Olivia, Zhang, Weiguo
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2004
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211849/
https://ncbi.nlm.nih.gov/pubmed/15477350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041223
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