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Negative Regulation of Mast Cell Signaling and Function by the Adaptor LAB/NTAL
Engagement of the Fcɛ receptor I (FcɛRI) on mast cells and basophils initiates signaling pathways leading to degranulation. Early activation events include tyrosine phosphorylation of two transmembrane adaptor proteins, linker for activation of T cells (LAT) and non–T cell activation linker (NTAL; a...
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| Main Authors: | , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2211846/ https://ncbi.nlm.nih.gov/pubmed/15477348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041213 |
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