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Protein aggregation processes: In search of the mechanism

Amyloid formation typically follows a time course in which there is a long lag period followed by a rapid formation of fibrils. In this review, I show that the standard mechanisms of polymerization need to be expanded to consider that the monomeric proteins/peptides involved in amyloid formation are...

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Detalhes bibliográficos
Autor principal: Frieden, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211696/
https://ncbi.nlm.nih.gov/pubmed/17962399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073164107
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