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The search for local native-like nucleation centers in the unfolded state of β-sheet proteins

An approach involving the systematic computational conformational analysis of all overlapping hexapeptide segments in the protein sequence has found fragments with the higher than average propensity to adopt the native-like three-dimensional structure and other regular nonrandom structures in the un...

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Detalhes bibliográficos
Main Authors: Nikiforovich, Gregory V., Frieden, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124924/
https://ncbi.nlm.nih.gov/pubmed/12140369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162362199
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