Effect of selective cyclooxygenase-2 (COX-2) inhibitor treatment on glucose-stimulated insulin secretion in C57BL/6 mice

Previous studies have shown that Prostaglandin E(2) (PGE(2)) inhibits glucose-stimulated insulin secretion. However, the role of cyclooxygenase (COX)-1 vs. COX-2 derived PGE(2) production in glucose-stimulated insulin secretion remains poorly understood. Here we investigated the expression of COX-1...

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Hlavní autoři: Fujita, Hiroki, Kakei, Masafumi, Fujishima, Hiromi, Morii, Tsukasa, Yamada, Yuichiro, Qi, Zhonghua, Breyer, Matthew D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211567/
https://ncbi.nlm.nih.gov/pubmed/17825788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.08.090
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