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BIOERODIBLE DEVICES FOR INTERMITTENT RELEASE OF SIMVASTATIN ACID

The association polymer system of cellulose acetate phthalate (CAP) and Pluronic F-127 (PF-127) was used to create intermittent release devices for mimicking the daily injection of simvastatin that has been reported to stimulate bone formation. To enhance solubility in water, prodrug simvastatin was...

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Autors principals: Jeon, Ju Hyeong, Thomas, Mark V., Puleo, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211564/
https://ncbi.nlm.nih.gov/pubmed/17433584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2007.03.007
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