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BIOERODIBLE DEVICES FOR INTERMITTENT RELEASE OF SIMVASTATIN ACID
The association polymer system of cellulose acetate phthalate (CAP) and Pluronic F-127 (PF-127) was used to create intermittent release devices for mimicking the daily injection of simvastatin that has been reported to stimulate bone formation. To enhance solubility in water, prodrug simvastatin was...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2211564/ https://ncbi.nlm.nih.gov/pubmed/17433584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2007.03.007 |
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