Nalaganje...

Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter

BACKGROUND: Internal polymerase III promoters in retroviral vectors have been used extensively to express short RNA sequences, such as ribozymes, RNA aptamers or short interfering RNA inhibitors, in various positions and orientations. However, the stability of these promoters in the reverse orientat...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Braun, Stephen E, Shi, Xuanling, Qiu, Gang, Wong, Fay Eng, Joshi, Pheroze J, Prasad, Vinayaka R, Johnson, R Paul
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211285/
https://ncbi.nlm.nih.gov/pubmed/17941994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-4-24
Oznake: Označite
Brez oznak, prvi označite!