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Molecular plasticity of β-catenin: New insights from single-molecule measurements and MD simulation

The multifunctional protein, β-catenin, has essential roles in cell adhesion and, through the Wnt signaling pathway, in controlling cell differentiation, development, and generation of cancer. Could distinct molecular forms of β-catenin underlie these two functions? Our single-molecule force spectro...

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Autori principali: Ritco-Vonsovici, Monica, Ababou, Abdessamad, Horton, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley-Blackwell 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206973/
https://ncbi.nlm.nih.gov/pubmed/17660262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072773007
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