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The first step of hen egg white lysozyme fibrillation, irreversible partial unfolding, is a two-state transition

Amyloid fibril depositions are associated with many neurodegenerative diseases as well as amyloidosis. The detailed molecular mechanism of fibrillation is still far from complete understanding. In our previous study of in vitro fibrillation of hen egg white lysozyme, an irreversible partially unfold...

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Autores principales: Xu, Ming, Shashilov, Victor A., Ermolenkov, Vladimir V., Fredriksen, Laura, Zagorevski, Dmitri, Lednev, Igor K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206649/
https://ncbi.nlm.nih.gov/pubmed/17400924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062639307
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