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Exploring subdomain cooperativity in T4 lysozyme II: Uncovering the C-terminal subdomain as a hidden intermediate in the kinetic folding pathway

Intermediates along a protein's folding pathway can play an important role in its biology. Previous kinetics studies have revealed an early folding intermediate for T4 lysozyme, a small, well-characterized protein composed of an N-terminal and a C-terminal subdomain. Pulse-labeling hydrogen exc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cellitti, Jason, Bernstein, Rachel, Marqusee, Susan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206637/
https://ncbi.nlm.nih.gov/pubmed/17400925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062632807
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