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Evolution of GITRL immune function: Murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily

Glucocorticoid-induced TNF receptor ligand (GITRL), a recently identified member of the TNF superfamily, binds to its receptor, GITR, on both effector and regulatory T cells and generates positive costimulatory signals implicated in a wide range of T cell functions. In contrast to all previously cha...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chattopadhyay, Kausik, Ramagopal, Udupi A., Brenowitz, Michael, Nathenson, Stanley G., Almo, Steven C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206588/
https://ncbi.nlm.nih.gov/pubmed/18182486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710529105
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