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Allosteric cooperativity in protein kinase A
Allosteric signaling in proteins requires long-range communication mediated by highly conserved residues, often triggered by ligand binding. In this article, we map the allosteric network in the catalytic subunit of protein kinase A using NMR spectroscopy. We show that positive allosteric cooperativ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206566/ https://ncbi.nlm.nih.gov/pubmed/18178622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709214104 |
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